Commissioning of Onasemnogene Abeparvovec (Zolgensma) Gene Therapy Services for Spinal Muscular Atrophy

Awarded 29 Apr 2021

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Ended 1y 6mo ago4y term
Awarded 29 Apr 2021Expired 28 Apr 2025

NHS Arden and Greater East Midlands Commissioning Support Unit awarded a contract to University Hospitals Bristol and Weston NHS Foundation Trust, Guy's and St Thomas' NHS Foundation Trust, Manchester University Hospitals Foundation Trust, and Sheffield Children's NHS Foundation Trust for the delivery of Onasemnogene abeparvovec (Zolgensma) gene therapy services for children with spinal muscular atrophy.

The contract, valued at £6,000,000, covers the provision of a single-use gene replacement therapy administered intravenously, requiring providers to have a neuromuscular multidisciplinary team, experience in treating children with SMA, and the capability to safely manage the product in line with containment level 1 requirements.

Providers are expected to operate as a national MDT to ensure eligible patients are treated within appropriate timescales, with an anticipated 25 to 35 children requiring treatment annually.

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