Tender: Pharmacogenomic (PGx) Testing Service for 4,854 Participants in Londonderry, Tyrone, Donegal and Sligo

About

The project is seeking a laboratory or multiple laboratories to provide an end-to-end pharmacogenomic testing service delivering genomic variant data for 4,854 participants recruited from GP practices in counties Londonderry and Tyrone (Northern Ireland) and Donegal and Sligo (Ireland). The service will support the iMPROVE research implementation study to integrate pharmacogenomic testing into a patient-centred medicines optimisation care pathway led by GP practice pharmacists, aiming to reduce inappropriate or ineffective treatments and lower adverse drug event risk. Required services include transport of participant samples from GP sites and testing for a finite list of single nucleotide polymorphisms (SNPs) that alter metabolism rates for a constrained list of prescribed medications, including opioids, SSRIs, PPIs, statins and clopidogrel.